Under the Skin – Mesotherapy and Dermarolling Techniques with Concentrated Serums - Challenging Times Call for Advanced Treatments by Deborah Tosline

Deborah Tosline wrote and published Skin Remodeling DIY: An Introduction to the Underground World of Do-It-Yourself Skincare in 2015. Deborah's education and work experience is in science, where hypotheses are tested through observation and experiments. She has Bachelor of Science degrees in geology and ecology. Her approach to skin care is based on that scientific background, a love of research and over 30 years of DIY skincare experience.
Anatomy The Skin - NCI Visuals Online By Don Bliss (artist) [Public domain], via Wikimedia Commons

Anatomy The Skin - NCI Visuals Online By Don Bliss (artist) [Public domain], via Wikimedia Commons

Click on the blue-green words for internet links.

Is it possible to radically improve skin vibrancy using Mesotherapy techniques combined with concentrated skin care serums? I think so, don’t know yet and am excited to find out. Here’s why.


I discovered vitamin C’s super healing powers several decades ago when I mega-dosed during a cold. I probably dosed 3,000 to 5,000 milligrams per day (mg/d); today I mega-dose 5,000 to 10,000 mg/d. The Vitamin C Foundation recommends taking vitamin C to bowel tolerance, when your intestines rumble that’s your limit. 

Crystals of vitamin C By Doc. RNDr. Josef Reischig (http://creativecommons.org/licenses/by/3.0)], via Wikimedia Commons

Crystals of vitamin C By Doc. RNDr. Josef Reischig (http://creativecommons.org/licenses/by/3.0)], via Wikimedia Commons

You might ask:

Is mega-dosing Vitamin C dangerous?  No, vitamin C as ascorbic acid is water soluble, any excess is excreted.

Is this hard on the liver?  My doctor recently told me that I have the liver enzyme levels of a teenager (I am 58).

Is it wasteful?  My recovery is speedy, so… not to me.

What happened to my skin the first time that I mega-dosed Vitamin C?  My skin looked incredible! Amazing! Bright!

I became a confirmed fan of vitamin C.

I mega-dose intermittently, as needed. I consume vitamin C daily in several forms. Vitamin C is essential for biochemical functions, promotes production of collagen and elastin and so much more, like any good anti-oxidant.

In the late 1980’s, I began taking anti-oxidants as “insurance” against free radical damage and for health. I continue to consume and apply vitamins, nutrients and other constituents daily for optimum health. I take a break one day a week or one week a month and vary my nutraceutical menu based on desire and needs.

My point:

I can feel the vitality of ingesting vitamins and I have a progressive and evolving yearning to support a nutrient rich lifestyle. This led me to seek out and try the variety of methods that folks use to optimize health (= beauty).

Mesotherapy and Dermaroller Mesotherapy

There’s another way to introduce vitamins into your system, under the skin.

Mesotherapy micro-needles inject plant extracts, homeopathy, pharmaceuticals, vitamins, and other bioactive substances beneath the epidermis and dermis to treat medical and cosmetic conditions. Dermaroller Mesotherapy creates miniscule channels into the epidermis or dermis allowing for instantaneous penetration of pure, concentrated, nutrient rich serums.

The Mesotherapy technique was developed in 1952 by French physician, Dr. Michel Pistor and has a history of use for the management of pain and vascular disorders.

By National Institutes of Health [Public domain], via Wikimedia Commons

By National Institutes of Health [Public domain], via Wikimedia Commons

Mesotherapy micro-injections and Dermaroller Mesotherapy promote instant absorption of highly concentrated serums in targeted locations for local diffusion and rapid results.

dermaroller needle sizes http://dermarollerqmd.com/wp-content/uploads/2016/02/dermaroller-needle-sizes.jpg

dermaroller needle sizes http://dermarollerqmd.com/wp-content/uploads/2016/02/dermaroller-needle-sizes.jpg

Laboratory research is limited and the results of this study showed neutral results in facial skin using Mesotherapy. Practitioners think the study may have been too small to accurately assess the practice.

Anecdotal evidence by Mesotherapy and Dermaroller Mesotherapy practitioners indicates that the practice is known to boost cellular regeneration and effectively promote skin health and overall appearance.

DIY Mesotherapy via Dermarolling

Internet stores make it is possible to purchase do-it-yourself (DIY) Mesotherapy kits containing a dermaroller device and vitamin concentrates or antioxidant cocktails that may profoundly revitalize the skin. Based on my experience, it is possible to promote skin remodeling or rejuvenation by enhancing skin health using intense nourishment and advanced skin care practices.

I have not tried nor am I affiliated with either of the companies listed below, although they do look particularly interesting to me.

Laboratories Surface-Paris distribute at-home MESO-GLOW and MESO-BRIGHT mesotherapy treatments that deliver a meso-roller with a concentrated dose of vitamins and hyaluronic acid serum that promise to illuminate and intensely hydrate the skin.

Lipostabil-DIY.com sells an interesting Derma Roller Kit that contains one 0.5 millimeter (mm) Derma Roller with 540 microneedles and vials of DNA Liquid and Dexpanthenol. Guaranteed to promote healthy skin.

Curious about DNA Liquid and Dexapanhenl?

DNA Liquid is a natural polymer anti-oxidant that promotes collagen. Dexpanthenol is Pantothenic acid, essential to skin function. 

The most important aspect of applying any skin product is purity. Mesotherapy and Dermarolling result in rapid skin absorption. Before using these techniques, always test any new products on a patch of skin and observe for evidence of an allergic reaction for 24 hours.

If you are not ready to try DIY Mesotherapy, check to see if there are reputable facilities near you.

By ER and Jenny (https://creativecommons.org/licenses/by-sa/2.0)], via Wikimedia Commons   

By ER and Jenny (https://creativecommons.org/licenses/by-sa/2.0)], via Wikimedia Commons


For now, I began my DIY Dermarolling Mesotherapy treatment using a 0.015 mm dermaroller (an oldie but a goodie with little use) with an oil based vitamin C, aloe vera leaf gel or raw organic honey covered by a piece of nori sushi seaweed. This is my  “gotta have it now” Dermarolling Mesotherapy treatment hack. It’s good. So, so good.

Take good care of yourself and for more skin care tips get my book "Skin Remodeling DIY: An Introduction to the Underground World of Do-It-Yourself Skincare" xo Deborah


This information is intended to be used as general information only and is in no way intended to replace medical advice, be used as a medical treatment program, diagnosis, or cure of any disease or medical condition. There are no warranties, expressed or implied, regarding the effectiveness of the practices described here. Products or substances discussed herein are for educational purposes only and are not intended as recommendations of the author or publisher.